STAT ECG Diagnoses: differential for ST segment depression in the anteroseptal leads

ECG Weekly Workout with Dr. Amal Mattu


A 36-year-old woman with a past medical history of rheumatoid arthritis presents to the ED with 3 days of waxing and waning chest tightness. The pain is pleuritic and 4/10 in intensity. It is associated with mild dyspnea. There is no diaphoresis, vomiting or radiation of the pain. She feels improved with a GI cocktail. The following ECG is obtained:

Before watching this week’s video, ask yourself these questions:

  1. What ECG abnormalities do you notice?
  2. What is your differential diagnosis?
  3. How would you treat this patient?