Killer Differentials

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T Wave Inversion in V1-V3 DDx

Key Points Common Misconception: T-wave inversions (TWIs) in V1–V3 are often prematurely labeled as “anteroseptal ischemia,” but there’s a much broader differential. Essential Differentials: Pulmonary causes (e.g., PE), Arrhythmogenic RV…

LVH vs STEMI: DDx

Key Points LVH Mimicry: Left ventricular hypertrophy (LVH) can mimic anterior coronary occlusion and is a common cause of “false-positive” cath lab activations. Diagnostic Challenge: LVH with strain pattern can…

Early Repolarization vs STEMI: DDx

Key Points Differentiation Challenge: Early repolarization (ER) is a benign ECG pattern often seen in healthy young individuals, characterized by ST segment elevation that can mimic STEMI and acute pericarditis….

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