Key Points: Definition: Hypertrophic cardiomyopathy (HCM) is characterized by otherwise unexplained LV hypertrophy. In obstructive HCM, septal hypertrophy plus systolic anterior motion (SAM) of the mitral valve produces dynamic left…
Key Points: Definition: Apical hypertrophic cardiomyopathy (ApHCM) is an HCM phenotype in which hypertrophy predominantly involves the LV apex. Signature ECG: High QRS voltage with deep, symmetric T-wave inversion, classically…
A 51-year-old truck driver presents to the ED after a brief syncopal episode at a rest stop. It is the middle of summer, his truck’s air conditioning is not working,…
Key Points: Posterior OMI can hide on the standard 12-lead. Acute posterior coronary occlusion may produce no diagnostic ST elevation in the conventional leads. Instead, posterior ST elevation is seen…
Key Points: Not a PE diagnosis: S1Q3T3 is classically associated with pulmonary embolism, but it is neither sensitive nor specific enough to diagnose or exclude PE. Think acute right heart…
Key Points: The ECG cannot rule in or rule out PE: No single ECG finding is sufficiently sensitive or specific to diagnose or exclude acute pulmonary embolism. A Normal ECG…
Key Points: The ECG can provide an early warning of severe RV strain: No ECG finding defines high risk PE, but marked or evolving signs of acute RV pressure overload…
A 69-year-old woman presenting with sepsis gets the following ECG for tachycardia while febrile and shivering. The baseline is poor, atrial activity is difficult to identify, and the computer interpretation…
Key Points: Early repolarization (ER) is one of the most common non-ischemic causes of ST elevation and one of the most frequent ECG mimics of acute anterior coronary occlusion. The…
A 56-year-old man presents with 1 week of concerning chest pain and shortness of breath. His ECG does not meet conventional STEMI criteria, but it shows subtle ST-segment abnormalities in…
A 34 year old man presents with acute chest pain radiating to the left arm associated with diaphoresis. He has hyperlipidemia and a family history of early coronary disease. The…
Key Points: Definition: ECG artifact is a noncardiac signal that distorts, obscures, or mimics the heart’s true electrical activity. Common sources: Patient movement or muscle activity, poor electrode contact, lead…
Key Points: What It Is: Brugada syndrome is an inherited arrhythmogenic disorder associated with ventricular fibrillation (VF), polymorphic VT, and sudden cardiac death, often in patients without obvious structural heart…
Key Points: The Barcelona Criteria are ECG criteria proposed to identify acute myocardial infarction in patients with LBBB. Core problem: LBBB causes expected secondary ST-T changes, so standard STEMI millimeter…
Key Points: Aslanger pattern is an OMI pattern that can identify acute inferior occlusion despite not meeting traditional STEMI criteria. The key finding is ST segment elevation isolated to lead…
Key Points: LBBB does not exclude acute coronary occlusion. LBBBs produce abnormal depolarization and expected secondary ST-T changes, which can mask or mimic ischemia. Acute occlusion MI can still be…
Key Points: What It Is: Severe hyperkalemia can cause sudden, profound, symmetric muscle weakness or flaccid paralysis. Dr. Mattu has referred to this memorable presentation as “Impressive Syndrome,” a teaching…
A 72-year-old man is brought to the ED after witnessed cardiac arrest. Bystander CPR was started quickly, EMS found a nonshockable rhythm, epinephrine was given, and ROSC was achieved. Forty…
Key Points: The first post-ROSC ECG is essential but imperfect. Obtain it immediately, but interpret it in context. Global ischemia, defibrillation, acidosis, hypothermia, vasopressors, artifact, and severe metabolic derangements can…
Key Points: Persistent ST elevation after ROSC remains a guideline-supported indication for emergency coronary angiography. The 2025 ACC/AHA/ACEP/NAEMSP/SCAI ACS guideline recommends emergency angiography for patients after cardiac arrest with suspected…